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Osseointegration aspect of implants placed in bone reconstructed site with novel porous titanium
EAO Online Library. Kobatake R.
Oct 9, 2018; 232539
Reiko Kobatake
Reiko Kobatake
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Abstract
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After bone resection surgery, bone defects accompanied with loss of teeth, it is required not only bone reconstruction but also occlusal function by prosthesis such as dental implant. The authors have revealed that novel porous titanium (Ti) has good mechanical strength and osteoconductivity because of three-dimensional structure. The purpose of this study was to evaluate the osseointegration abilities of implants placed in novel porous Ti.For the bone reconstruction material, porous Ti (φ+6 mm in outer, φ+2 mm in inner diameter×4 mm, hollow cylindrical shape) fabricated by Ti impregnation technique. The same shape of porous hydroxyapatite was used as control. **Bone defect (φ+6mm×4mm) were prepared in both femurs of male New Zealand White rabbits (17 weeks old) and each graft material was placed (n=4). Four weeks after first surgery, an implant socket was prepared in the hollow part of the graft material, and a pure Ti implant (φ+2 mm×4 mm) was implanted. Four weeks after implantation, non-decalcified specimens were prepared, and toluidine blue staining was applied. We performed the histological observation and histomorphometric evaluations+ bone formation ratio and bone implant contact ratio (BIC) (n=4).**All data were statistically analyzed at the 5% significance level using Students’T test.**(Approved by Hiroshima University animal experiment ethics committee- A11-5-5)**New bone formation was observed in both groups, and there is no significant difference in bone formation ratio. Also, osseointegration was observed at the bone-implant interface, and BIC was also no significant difference. Novel porous Ti has good mechanical strength and enough for bone formation scaffold. Moreover, it could be able to achieve osseointegration at bone reconstructed site by the porous Ti.
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